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  • DNA binding and dimerisation determinants of Antirrhinum majus MADS However, the K-box in SQUA can also act as an oligomerisation motif and in the full-length protein, the K-box plays a different role in mediating dimerisation in the context of SQUA homodimers or heterodimers with PLE. — “ingentaconnect DNA binding and dimerisation determinants of”,
  • Selective dimerisation of -olefins using tungsten-based initiators The catalyst is found to be highly selective towards dimerisation, minimising the formation of undesired heavier oligomers. — “Dalton Transactions Articles”,
  • Dimerisation of HIV-2 genomic RNA is linked to efficient RNA packaging, normal particle maturation and viral infectivity HIV-2 RNA dimerisation is thought to occur at the dimer initiation. — “Dimerisation of HIV-2 genomic RNA is linked to efficient RNA”, m.nih.gov
  • This dimerisation domain is found at the C terminus of the IPR008906 HAT dimerisation 638 - 720. P12258 Transposable element Hobo transposase. — “IPR008906 HAT dimerisation”,
  • The dimerisation step itself may be carried out as described in European patent 108638 and WO 98/23296, for example using epichlorohydrin as the dimerisation agent. The crude product from the dimerisation and following work-up steps. — “Crystallization of iodixanol in isopropanol and methanol”,
  • 1H6O: Structure of the Trfh Dimerization Domain of the Human Telomere Proteins Trf1 and Trf2 DIMERISATION DOMAIN RESIDUES 63-265. Source. Hide. Polymer: 1. Scientific Name: Homo sapiens. — “RCSB Protein Data Bank - Structure Summary for 1H6O”,
  • βI, promotes dimerisation of the native structure rather than The fact that dimerisation occurs. through this. β-strand shows the value of the method. for. — “Competition between Folding, Native-State Dimerisation and”, www-
  • Definition of Dimerisation in the Medical Dictionary. Dimerisation explanation. Information about Dimerisation in Free online English dictionary. What is Dimerisation? Meaning of Dimerisation medical term. What does Dimerisation mean?. — “Dimerisation - definition of Dimerisation in the Medical”, medical-
  • The SCOP classification for the Transferrin receptor-like dimerisation domain superfamily including the families contained in it. Additional information provided includes InterPro annotation (if available), Functional annotation, and SUPERFAMILY. — “Transferrin receptor-like dimerisation domain superfamily”,
  • As the dimerisation of the acid is probably an ionic process, the radical inhibitors The stabilisation of the acid against dimerisation in the presence of thiocarbohydrazide implies the intervention of the thiocarbohydrazide-acid complex in the dimerisation process. — “Thiocarbohydrazide as inhibitor for the liquid- and gas-phase”,
  • monomeric fragment, lacking the C-terminal dimerisation domain, showed A dimerisation interface is pro- posed to be formed by the exposure. — “Independent ATPase Activity of Hsp90 Subunits Creates a”, www-
  • Articles tagged with: Dimerisation. Still In The RBF " Helicterin B, Helisorin, and cycloaddition cyclopropation Diels-Alder Dimerisation epoxidation Epoxide Heck Hetero. — “ " Dimerisation”,
  • The reverse of dimerisation is often called dissociation. [edit] Biochemistry. In biochemistry and molecular biology, dimers of macromolecules like proteins and nucleic acids are often observed. The dimerization of identical subunits is called. — “Dimer - Wikipedia, the free encyclopedia”,
  • characterisation of HPr did not mention any dimerisation is tempting to speculate that dimerisation of Crh occurs. when P-Ser-Crh interacts with. — “Evidence for a Dimerisation State of the Bacillus subtilis”,
  • It has now been found that tertiary-butylmethyl ether can be used in an improved process to give high yields of Grignard products and with a very low amount of dimerisation in reactions using magnesium and starting materials in equimolar or nearly equimolar amounts. — “(WO/1993/012121) PROCESS FOR THE PREPARATION OF ETHER”, wipo.int
  • News and project information on the Pertuzumab –Cancer Therapy. Pertuzumab also targets the HER2 receptor but as a HER dimerisation inhibitor, or HDI, it inhibits the dimerisation or 'pairing' of the HER2 protein with other members of the HER family of receptors: HER1/EGFR, HER3 and HER4. — “Pertuzumab –Cancer Therapy - Drug Development Technology”, drugdevelopment-
  • These mutants showed much reduced actin binding, although they did bind to actin significantly better than the polypeptide lacking the entire dimerisation domain (Table I), suggesting that the dimerisation domain may also interact with actin. — “The structure of the C-terminal actin-binding domain of talin”,
  • Although Wunen, a Drosophila lipid phosphate phosphatase that plays a role in germ cell migration and loss, can form dimers both in vitro and in vivo, dimerisation is not essential for in vivo activity, contrary to some speculation. — “BioMed Central | Full text | Lipid phosphate phosphatases”,
  • Definition of Dimerisation in the Online Dictionary. Meaning of Dimerisation. Pronunciation of Dimerisation. Translations of Dimerisation. Dimerisation synonyms, Dimerisation antonyms. Information about Dimerisation in the free online English. — “Dimerisation - definition of Dimerisation by the Free Online”,

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  • Roche Personalised Healthcare - Structure Roche is uniquely positioned to make Personalised Healthcare a reality. Its structure affords access to a broad range of Diagnostic and Pharma technologies and capabilities to systematically pursue this approach across the entire value chain.
  • Lecture - 16 Immobilized Enzymes - III Lecture Series on Enzyme Science and Engineering by Prof.Subhash Chand, Department of Biochemical Engineering,IIT Delhi. For more details on NPTEL visit nptel.iitm.ac.in
  • Roche Personalised Healthcare - Mission At Roche, 'Personalised Healthcare' is at the core of our business strategy. Our expanding knowledge and understanding of disease mechanisms combined with our molecular biology and technology expertise, are leading us to more targeted therapies, and clinically differentiated products.
  • Toronto & Waterloo team presentation at iGEM 2006 The Cell-See-Us thermometer is a gene construct that produces differing amounts of green and red fluorescing proteins in response to temperature changes. The functionality of the Cell-See-Us thermometer is based on the dimerization of a temperature sensitive LacI protein (BBa_J06501). This protein is produced in dimer form, which exists in equilibrium with its tetramer form. Modifying the environmental temperature (ie. of the cellular host) will cause a noticeable shift in this equilibrium. At low temperatures, there is a high ratio of LacI ts tetramers to dimers. In the thermometer construct, the tetrameric form of the LacI binds to and represses the pLac promoter (which is actually a pL promoter with LacI sites, forming an effective pLac-like repressor). This prevents the transcription of the tetR gene. In turn, the lack of tetR protein production will allow the pTet promoter immediately downstream to upregulate the expression of green fluorescent protein (GFP). At the same time, the second pLac in the construct will also be repressed, and since it drives monomeric red fluorescent protein (mRFP) production, there will be a decrease in intracellular levels of mRFP. The amount of GFP produced relative to the amount of mRFP will result in net green fluorescence. Conversely, when cells containing the thermometer are exposed to high temperatures, LacI will predominately exist in the dimer form. With a lower intracellular concentration of tetramers, repression of the pLac ...
  • The Highs and Lows of EGFR The binding of epidermal growth factor (EGF) induces dimerization and activation of its receptor, EGFR. Watch as Mark Lemmon and Diego Alvarado take you on a brief, personally guided tour of their findings that low-affinity receptors are generated by asymmetric ligand binding and negative cooperativity.
  • Roche Personalised Healthcare - Achievements 'Personalised Healthcare' goes beyond just companion diagnostics. Today, Roche is already offering more precise diagnosis and targeted treatments. Our accomplishments are many, especially in oncology and virology, and the pipeline is full.
  • Human insulin receptor tyrosine kinase in active conformation with IRS1 pYMXM site in its mouth Stevan Hubbard's Xray crystallographic data (pdb 1IR3) were taken to generate a ribbon diagram using PyMol. The N-lobe of the protein is colored in aqua and pastel blue, and found at the top of the frame in the movie. The C-lobe is colored in yellows, spring green, orange and red, and located at the bottom half of the frame. The substrate YMXM segment (a peptide derived from IRS1) is colored as a black "insect" trapped in the maw of the substrate cleft. Two Mg++ ions chelating ATP in the ATP binding pocket are shown as yellow balls. The 3 pTYR residues on the yellow activation loop (A-loop) are painted white. Notice that the white/yellow A-loop is swung away almost on the opposite site of the TK domain from the black substrate. Presumably, in the native activated holoreceptor, the white pTYR residues in the beta subunits face each other in dyad symmetry on a TK dimer interface. The black insects (substrate, and thus IRS1) would be located distally flanking the "wings" of the TK dimer.
  • 13.1.2 Describe the reactions of chlorine/chlorides referred to in 13.1.1 with water IB Chemistry HL Everything produces HCl when added to water, so all the the chloride are acidic EXCEPT NaCl, which is neutral in solution. This all makes more sense after studying acids and bases.
  • Lewis X dimerisation Computational studies of the dimerization process and the influence of calcium ion
  • Thymine Dimer The covalent bonding of two adjacent thymine residues within a DNA molecule, often catalyzed by ultraviolet radiation or chemical mutagenic agents.
  • Advantages of Personalised Healthcare Daniel O'Day, Chief Operating Officer of Roche Diagnostics and Richard Scheller, Executive Vice President of Genentech Early Research and Development discuss the growing collaboration between their two organizations. At Roche the 'Personalised Healthcare' strategy is a core element of the company's approach to develop new tests and medicines. The close collaboration between its Pharmaceuticals and Diagnostics divisions is fundamental for Roche's long-term success.
  • Elementary Productions: Flash freezing Nitrogen Dioxide Nitrogen Dioxide, as we know it, exists in equilibrium with many other Oxides of Nitrogen. These equilibriums are very affected by temperature, and in this video we'll see what happens when you flash freeze a sample of Nitrogen Dioxide
  • TLR4-MD-2-LPS complex Structure of Toll-like Receptor 4 multimer constructed in Pymol.
  • VEGF and EGFR pathways in detail: Target for new therapies against cancer Mechanism of action of VEGF (vascular endothelial growth factor) and EGFR (epidermal growth factor receptor) signalling pathways. Mécanisme d'action des voies de signalisation du VEGF et de l'EGFR. EFP Website: www.efp-. European Fellowship for Pharmacists
  • The Estrogen Receptor (II): Molecular & Cellular Mechanisms A 3D animation illustrating the estrogen mechanism at cellular and molecular levels. Credits: Animation created by: Tiffany Chow Vassar College, class of 2007 Original concept and script by: Dr. Janet Gray Psychology Department Science, Technology and Society Program Vassar College and Cristián Opazo Academic Computing Services, Vassar College Voiceover by: Dede Hourican Academic Technology and e-Learning, Marist College Copyright © 2005 by Vassar College. Do not reproduce, download or edit without permission.
  • DNA UV damage Formation of a Thymine dimer in DNA exposed to UV radiation.
  • Dynamic Equilibrium between Nitrogen Dioxide and Dinitrogen Tetroxide The reversible reaction between NO2 and N2O4 is exothermic on forming N2O4 and endothermic on forming NO2. LeChatelier prediicts that heating the mixture will favour the formation of NO2. (Adding energy assists the endothermic reaction and inhibits the exothermic reaction, changing the rates of the forward and backward reactions. Increasing the rate of one reaction more than the other changing the composition of the equilibrium mixture.
  • Amirsheraf: Whoever knows whats meant by 'dimerisation' pls dm me i can not google it for some reasons

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  • “PS3GRID/GPUGRID is a volunteer computing project based on the PlayStation3 or graphics cards (gaming and professinal hardware) for all-atom molecular dynamics simulations of proteins for biomedical research. We optimize our code for the Cell”
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  • “Peter MR's Blog. The Chem Blog. The Curious Wavefunction. The Sceptical Chymist. Community cycloaddition cyclopropation Diels-Alder Dimerisation epoxidation Epoxide Heck Hetero”
    — " Dimerisation,

  • “About this Blog | Book Homepage | Purchase the Book. Cyclopentyne-alkene cycloadditions. A nice follow-up to some of my own work an alkyne, which produces initially a ketocarbene, the dimerisation of a carbene to give an alkene, and some”
    — Computational Organic Chemistry " Cyclopentyne-alkene,

  • “The peroxidase- catalysed dimerisation of the opiate agonist met-enkephalin, is strongly Somni-Forum Regular. Group: Somniphiles. Posts: 107. Joined: 8-January 03. Member No.: 836”
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  • “Could be dimerisation of some of the indoles. Don't know what the colour of be promoted by oligoelements like manganese, as could dimerisation”
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  • “nirupama's blog. Review Article. Submitted by Nirupama Sita N on Sat, 07/12/2008 - 17:16 Growth factor binding leads to dimerisation of pairs of receptors. The association of the”
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